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Exploring global viral diversity with conserved sequence tags

Viruses control much of the world indirectly through infection of microbial cells. Modern metagenomics provides the raw data to investigate their dynamics and patterns of co-occurrence with the microbial hosts, but extracting signal from these datasets at the large scale remains challenging. Marker-gene based approaches, such as SingleM, have shown great promise for microbial data, converting metagenomic datasets into community profiles by concentrating on reads which derive from conserved sections of prevalent genes.

Study level
PhD
Faculty
1043076
School
School of Biomedical Sciences
Research centre(s)

Centre for Microbiome Research

Symbiosis in microbial ecosystems

Soil systems are fundamentally important to the health of our planet, but the complexity of soil microbial communities makes them particularly challenging to study. Soil systems are amongst the most diverse microbial ecosystems on Earth in terms of the number of microbial species (and strains) present within individual samples, and in the breadth of functions encoded. Beyond complexity measured by counting distinct community members, interactions between microbial species including symbiosis, parasitism or commensalism are widespread and yet barely studied.

Study level
PhD, Master of Philosophy, Honours
Faculty
1043076
School
School of Biomedical Sciences
Research centre(s)

Centre for Microbiome Research

Light, circadian rhythms and Parkinson’s disease

Up to 98% of patients with Parkinson’s Disease (PD) have non-motor symptoms (Poewe et al. Nature Rev Dis 2017, 3: 17013) and of those, circadian and sleep disorders are the most common (for review, Gros & Videnovic. 2020, Clin Geriatr Med 36: 119). These symptoms become increasingly prevalent during the course of PD and are key determinants affecting quality of life, advancement of overall disability and placement in nursing homes (Shapira et al. Nat Rev Neurosci 2017,18:435). Circadian and sleep …

Study level
PhD
Faculty
1043076
School
School of Biomedical Sciences

Can global geoengineering save the world's coral reefs?

At present, current actions and pledges by the world’s governments to limit greenhouse gas emissions are not sufficient to prevent dangerous changes in the climate system. These changes are projected to drive the destruction of almost all of the world's coral reef ecosystems.In response, global climate intervention strategies - such as stratospheric aerosol injection or marine cloud brightening - have been proposed to mitigate and delay the negative effects of climate change while efforts continue to reduce emissions. Yet, there …

Study level
Vacation research experience scheme
Faculty
Faculty of Science
School
School of Mathematical Sciences
Research centre(s)

Centre for the Environment

Discovering new species

Shotgun metagenomic sequencing has become commonplace when studying microbial communities and their relationship ship with the health of our planet, and their direct effects on our own health. Currently, there are >250,000 shotgun metagenomes publicly available, but until recently trying to treat these data as a resource has been challenging due to its extreme size (>1,400 trillion base pairs).We have developed a tool that can efficiently convert this base pair information into a straightforward assessment of which microorganisms are present …

Study level
Vacation research experience scheme
Faculty
Faculty of Health
School
School of Biomedical Sciences
Research centre(s)

Centre for Microbiome Research

Young drivers and the Australian Naturalistic Driving Study (CARR04)

The Australian Naturalistic Driving Study (ANDS) is a collaboration of road safety research centres across Australia. It uses a range of cameras, accelerometers, GPS and recording technology in participants’ own cars to record everyday driving on our roads.We have four months of data for 346 experienced drivers in NSW and Victoria. We recently added an average of 1,500 trips each for 15 newly licensed young drivers in NSW. We also have detailed cognition, behaviour and health assessments and surveys data …

Study level
Vacation research experience scheme
Faculty
Faculty of Health
School
School of Psychology and Counselling
Research centre(s)

Centre for Future Mobility/CARRSQ

Big data analysis to aid ecological research

We're looking for multiple students to help us answer the question: 'How can we utilise information technology to aid ecological research?'Sensor networks bring ecologists and pattern recognition researchers together to make some applications possible. These applications include assessing risks from potential bird collisions, unobtrusive observations (where the presence of humans changes some animal behaviours) and studying spatial and temporal variation in biological processes.With a significant amount of data being collected from these applications, processing and mining this data is challenging. …

Study level
PhD, Master of Philosophy, Honours
Faculty
Faculty of Science
School
School of Computer Science

Transport big data analytics: Imputing missing data

The missing data problem is often unavoidable for real-world data collection systems because of a variety of factors, such as sensor malfunctioning, maintenance work, transmission errors, and so on. Filling in missing information in a dataset is an important requirement for many machine-learning algorithms that require a complete dataset as input. Data imputation algorithms aim at filling the missing information in a dataset. Many missing data imputation techniques exist in the literature, with applications demonstrated on various types of datasets. …

Study level
PhD, Master of Philosophy, Honours, Vacation research experience scheme
Faculty
Faculty of Engineering
School
School of Civil and Environmental Engineering
Research centre(s)
Centre for Data Science

Contributions and risks of smart urban technology-driven approaches to sustainable development

The prospects of smart urban technologies range from expanding infrastructure capacity to generating new services, from reducing emissions to engaging the public, from minimising human errors to improved decision-making, and from supporting sustainable development to improving performances of commercial enterprises and cities. The most popular technologies in the context of cities include, but are not limited to:internet-of-things (IoT)autonomous vehicles (AV)Mobility-as-a-Service (MaaS)bigdata5G/6Groboticsblockchaincloud computing3D printingaugmented and virtual reality (AR/VR)digital twinsartificial intelligence (AI).These disruptive technologies are critical in transforming our cities into smarter …

Study level
PhD, Master of Philosophy, Honours, Vacation research experience scheme
Faculty
Faculty of Engineering
School
School of Architecture and Built Environment

Prostate cancer transcriptomics (Honours and Master of Philosophy)

At the Australian Prostate Cancer Research Centre QLD, we are interested in the cellular adaptive response processes leading to therapy resistance in advanced prostate cancer.A focus area of our research is studying the transcriptome changes in prostate cancer cell lines, xenograft models and patient samples using RNA sequencing technologies.By integrating our large in-house repository of RNAseq data sets with publicly available studies, this project will further explore the cellular heterogeneity of prostate tumours and the plasticity of cancer cells in …

Study level
Master of Philosophy, Honours
Faculty
1043076
School
School of Biomedical Sciences

Prostate cancer transcriptomics (BIOM02)

At the Australian Prostate Cancer Research Centre QLD we are exploring how cancer cells can adapt and reprogram to become resistant to treatment and thus enable progression to advanced disease.A focus area of our research is studying the transcriptome changes in prostate cancer cell lines, xenograft models and patient samples using RNA sequencing technologies. By integrating our own data sets with publicly available studies, we explore the cellular heterogeneity of prostate tumours and the plasticity of cancer cells in response …

Study level
Vacation research experience scheme
Faculty
Faculty of Health
School
School of Biomedical Sciences

Human data interaction with big data visual analytics

Our research is seeking to answer the question: 'How can we support human interaction with big data?'We want to integrate the outstanding capabilities of humans in terms of visual information exploration with the enormous processing power of computers. These elements have the capacity to form a powerful knowledge discovery environment. This research will use datasets from the Queensland Government and the QUT Ecoacoustic research group over multiple years. Other big datasets, such as Amazon’s product review dataset, could also be …

Study level
PhD, Master of Philosophy, Honours, Vacation research experience scheme
Faculty
Faculty of Science
School
School of Computer Science

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