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Development of 3D tumour models for radiobiological research

Approximately 40 percent of cancer patients will receive radiation therapy as part of the management of their disease. Radiation can be used alone or in combination with other treatment modalities such as surgery, chemotherapy, and increasingly immunotherapy.Optimising the delivery of radiation, to take advantage of new treatment planning and delivery techniques, or to test new combinations of treatment modalities in a pre-clinical setting, has traditionally been performed using single layer 2D cell cultures and small animal models.Recently, it has become …

Study level
Vacation research experience scheme
Faculty
Faculty of Engineering
School
School of Mechanical, Medical and Process Engineering
Research centre(s)
Centre for Biomedical Technologies

Integration of Indigenous knowledges and perspectives within the radiation therapy undergraduate curriculum

Radiation therapy (RT) graduates are required to have a combination of knowledge of Indigenous perspectives as well as highly technical and empathetic skills related to their practice.The aims of this study are to:provide a structured Indigenous knowledges curriculum that aligns with university graduate outcomes, and industry and registration requirementsinstil knowledge, skills, attitudes and awareness of Indigenous perspectives in the Radiation Therapy graduates using evidence informed approaches, so they can influence clinical practice by working in a culturally responsive manner to …

Study level
Vacation research experience scheme
Faculty
Faculty of Health
School
School of Clinical Sciences

Understanding the genetics of melanoma susceptibility: many roads lead to DNA repair

Repair of the damage caused by mutagens such as UV and reactive oxygen species is vital to prevent cancer and premature aging and accordingly cells have developed a suite of intricate and specific DNA repair pathways. Loss or abnormal function of components of these pathways lead to cancer pre-disposition syndromes for example breast cancer in individuals carrying mutations in the BRCA1 or BRCA2 genes. Understanding the complexities of these DNA repair pathways is vital to efforts aimed at preventing or …

Study level
Master of Philosophy, Honours
Faculty
Faculty of Health
School
School of Biomedical Sciences

Degradation-conscious charging of lithium-ion batteries

The adoption of electric vehicles and grid storage systems by the present day consumers has been phenomenal. The most critical issue with the lithium-ion (Li-ion) battery is how to manage its degradation.Understanding battery degradation mechanisms and the development of charging strategies to optimally manage battery degradation is very important. There are a number of important issues that need to be addressed carefully, such as thermo-electrochemical modelling of large battery packs and fast charging protocols.

Study level
PhD, Master of Philosophy
Faculty
Faculty of Engineering
School
School of Electrical Engineering and Robotics

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