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Found 49 matching student topics

Displaying 25–36 of 49 results

Illuminating the microbial world using genome-based fluorescence microscopy

Our understanding of microbial diversity on earth has been fundamentally changed by metagenomic characterisation of natural ecosystems. Traditional approaches for visualising microbial communities are time-consuming and provide limited information about the identity of specific microorganisms.The proposed research aims to combine single cell genomics and super resolution microscopy for novel, high-throughput, genome-based techniques to visualise microorganisms, plasmids and viruses, with strain level specificity.The application of these highly scalable approaches will provide comprehensive and unprecedented insight into the fine-scale dynamics and evolution …

Study level
PhD
Faculty
Faculty of Health
School
School of Biomedical Sciences
Research centre(s)

Centre for Microbiome Research

Spatial localisation of immunoglobulin A in the gastrointestinal tract.

Blood cancers, which include leukaemia, lymphoma and myeloma account for 10% of all cancers and 9.4% of cancer deaths. Stem cell transplantation (SCT) is the predominant curative therapy for these diseases. However, a major complication is graft-versus-host disease (GVHD) in which the gastrointestinal (GI) tract, skin, lung and liver are preferentially damaged by the transplanted donor immune system, limiting the therapeutic potential of this treatment. Thus, there is a pressing need for new treatment approaches to improve transplant outcome for …

Study level
Master of Philosophy, Honours
Faculty
Faculty of Health
School
School of Biomedical Sciences

Real-time Business Process Integration in the Industrial Internet of Things (IIoT) for Industry 4.0

The vision of Industry 4.0 is to support business capabilities at the edge. The Industrial Internet of Things (IIoT) enables this vision by integrating IoT with Enterprise Systems (ESs). In an IIoT process, sensor applications at the edge require seamless integration with the software services of ESs. This, in turn, facilitates the real-time correlation of sensor events with BPs. However, existing IIoT architectures lack the necessary architectural capabilities to reflect the true essence of Industry 4.0.This research aims to develop …

Study level
Honours, Vacation research experience scheme
Faculty
Faculty of Science
School
School of Information Systems

BIOM05 - Application of fluorescence microscopy for the visualization of methane-oxidizing microorganisms in the environment

The archaeal lineage Methanoperedenaceae are anaerobic methanotrophs with a key role in mitigating the atmospheric release of the potent greenhouse gas methane. The metabolic diversity of these microorganisms directly links methane with several key biochemical cycles and suggests a remarkable ability of these microorganisms to adapt to diverse environmental conditions.These microorganisms have never been grown in a laboratory and have only been studied in enrichment cultures with several other partner microorganisms. How these microorganisms grow and interact with these bacterial …

Study level
Honours, Vacation research experience scheme
Faculty
Faculty of Health
School
School of Biomedical Sciences
Research centre(s)

Centre for Microbiome Research

PSYC05 - Using EEG to investigate how the brain represents objects while they are temporarily invisible

In vision, objects are frequently occluded behind other objects, such as when a dog walks behind a fence. How does the brain represent objects that are either wholly or partially invisible? This project investigates this using an advanced new EEG analysis technique that we recently developed to decode the brain's visual predictions. We have previously used this new technique to show that the brain predicts what you are going to see, to allow you to see them more quickly, and …

Study level
PhD, Master of Philosophy, Honours, Vacation research experience scheme
Faculty
Faculty of Health
School
School of Psychology and Counselling

Sustainable energy transition with system dynamics

The challenge to keep global warming to 1.5°C above pre-industrial levels has become even greater due to a continued increase in greenhouse gas emissions (IPCC, 2023). One major challenge is the shift from fossil fuels to renewable energy to reduce emissions (Gholami et al., 2016). The share of renewable energy in electricity generation has increased to 28.3%, however, an acceleration of the pace of the transition is required to limit global temperature rise (REN21, 2022).New energy policies are needed to …

Study level
PhD, Master of Philosophy, Honours, Vacation research experience scheme
Faculty
Faculty of Science
School
School of Information Systems

Facilitating Towards Sustainable Electric Vehicles Trading System

The number of Electric Vehicles (EVs) on the road is expected to reach 145 million by 2030. As the number of EVs on the road increases, the demand for energy to charge these vehicles also grows. Traditional charging infrastructure may not meet the increasing energy demands, which may lead to increased waiting time in those charging stations. The EV-EV trading scheme is a promising solution that allows EV owners to access additional energy from nearby EVs. This scheme has attracted …

Study level
Honours, Vacation research experience scheme
Faculty
Faculty of Science
School
School of Information Systems

Image-based assessment of atherosclerotic plaque vulnerability: Towards a computational tool for early detection and prediction

Plaque characteristics and local haemodynamic/mechanical forces keep changing during plaque progression and rupture.Quantifying these changes and discovering the progression-stress correlation can improve our understanding of plaque progression/rupture. This will lead to a quantitative assessment tool for early detection of vulnerable plaques and prediction of possible ruptures.Our research project aims to combine medical imaging, computational modelling, phantom experiments and pathological analysis to investigate plaque progression and vulnerability to rupture in both animal models and patients with carotid stenosis.We will identify and …

Study level
PhD, Master of Philosophy, Honours, Vacation research experience scheme
Faculty
Faculty of Engineering
School
School of Mechanical, Medical and Process Engineering
Research centre(s)
Centre for Biomedical Technologies

Supercapacitor with 2D vertical heterostructure electrodes

Supercapacitor is a promising energy storage device with advantages of high power density, fast charging/discharging rate and long cycling life. However, the energy density of supercapacitor is relatively low as compared to that of other devices such as lithium-ion battery. To improve the energy density, new electrode materials including graphene and metal oxides have been explored for supercapacitor electrodes.Two-dimensional (2D) heterostructures recently offered a compelling solution to enhance the performance of supercapacitors by combining more than one components into a …

Study level
PhD
School
School of Mechanical, Medical and Process Engineering

Identifying emergent ecosystem responses through genes-to-ecosystems integration at Stordalen Mire

Permafrost thaw induced by climate change is predicted to make up to 174 Pg of near-surface carbon (less than 3m below the surface) available for microbial degradation by 2100. Despite having major implications for human health, prediction of the magnitude of carbon loss as carbon dioxide (CO2) or methane (CH4) is hampered by our limited knowledge of microbial metabolism of organic matter in these environments.Genome-centric meta-omic analysis of microbial communities provides the necessary information to examine how specific lineages transform …

Study level
PhD, Master of Philosophy, Honours
Faculty
Faculty of Health
School
School of Biomedical Sciences
Research centre(s)

Centre for Microbiome Research

2D heterostructures for future electronics

The traditional approach to the miniaturisation of electronic devices is coming to a halt. Experts agree that the Moore’s law prediction of doubling the number of transistors per chip every two years will cease to be fulfilled in 2020, as the heat produced in small structures cannot be cooled down quickly enough.However, by reducing the size of the device, the quantum nature of atoms and solids can be turned into an asset. By exploiting the phenomena occurring at these scales, …

Study level
PhD, Master of Philosophy, Honours, Vacation research experience scheme
Faculty
Faculty of Science
School
School of Chemistry and Physics
Research centre(s)
Centre for Materials Science
Centre for Clean Energy Technologies and Practices

Investigating DNA repair mechanisms in aging adult stem cells

When we age the DNA repair systems of our cells become down regulated. This results in reduced DNA repair capacity, enhanced rates of mutation load and may lead to the development of chronic aging-associated diseases including osteoporosis, Alzheimer's and cancer(1). So it is no surprise that genome instability and stem cell exhaustion, which also strongly correlates with the accumulation of DNA damage, are considered hallmarks of aging(2).However, we still lack a clear understanding on how the decrease in DNA repair …

Study level
PhD, Master of Philosophy, Honours
Faculty
Faculty of Health
School
School of Biomedical Sciences

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