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Detection of anti-Chlamydia antibodies in serum as a marker of testicular infection

Chlamydia trachomatis is an obligate intracellular, bacterial pathogen. C. trachomatis infections of the human reproductive tract affect approximately 127 million people globally each year. The major concern of C. trachomatis infections is their ability to cause infertility in both men and women, by damaging the upper reproductive tracts. Historically, Chlamydia has been considered more of a problem for women, but our recent research has shown the testes of men can be infected and this may contribute to idiopathic male infertility. …

Study level
Master of Philosophy, Honours
Faculty
Faculty of Health
Lead unit
School of Biomedical Sciences

Surgery robot

Significant advances have been made in surgical assistance robots, but significant challenges remain.This project will develop new systems for surgical assistance robots, including the potential for advanced surgical localization and positioning systems.This project is part of a major Australian Research Council Industrial Transformation Training Centre for Joint Biomechanics.

Study level
PhD, Master of Philosophy, Honours, Vacation research experience scheme
Faculty
Science and Engineering Faculty
Lead unit
School of Electrical Engineering and Robotics

Voluntary assisted dying, medical practitioners and conscientious objection

Should legislation permitting Voluntary Assisted Dying (VAD) provide medical practitioners with a right to conscientiously object to VAD and, if so, what should the scope of that right be?Should it include a right not to give a person asking about VAD any information about it? In Victoria the legislation provides an unrestricted right to conscientiously object whereas in Western Australia the right to object is qualified by a requirement to give the patient information about VAD. Which position is most …

Study level
PhD
Faculty
Faculty of Law
Lead unit
Australian Centre for Health Law Research

Use of depth sensing technology in radiotherapy and medical imaging

Consumer-grade depth sensing technology has in recent years become widely available. A number of vendors have developed similar technologies.Some examples of these technologies include:Intel’s RealSense™Asus Xtion depth sensorQualcomm Spectra ISP platform, now in its second generation.The systems make use of camera technology that measures the distance to a surface. Rapid image acquisition can then enable real time motion detection of location of the surface. The infra-red transmitter and sensor use a time-of-flight method to construct a depth map, in millimetres, …

Study level
PhD, Master of Philosophy, Honours, Vacation research experience scheme
Faculty
Science and Engineering Faculty
Lead unit
School of Electrical Engineering and Robotics

Develop point-of-care microfluidic technologies for cardiovascular and cerebrovascular diseases

Excessive clotting (thrombosis) leads to the cardiovascular diseases such as heart attack and stroke, killing one Australian every 12 minutes. It has long been recognized that platelets play a central role in thrombosis and are unique in their ability to form stable adhesive interactions under conditions of rapid blood flow.We've recently discovered a new ‘biomechanical’ prothrombotic mechanism that highlights the remarkable platelet sensitivity to the shear stress gradients of blood flow disturbance. Importantly, we've found that current anti-thrombotic drugs, such …

Study level
PhD, Master of Philosophy, Honours, Vacation research experience scheme
Faculty
Science and Engineering Faculty
Lead unit
School of Mechanical, Medical and Process Engineering

Development of 3D tumour models for radiobiology applications

There is increasing interest in developing 3D tumour models for use in cancer research. The models have been used to investigate and test novel therapies in a model that is closer to the in-vivo tumour micro-environment. So far there has been little investigation of their use for therapeutic interventions that include ionising radiation. This research will investigate how they may be used for studying the fundamental radiobiology of radiotherapy treatments for cancer.

Study level
PhD, Master of Philosophy, Honours, Vacation research experience scheme
Faculty
Science and Engineering Faculty
Lead unit
School of Mechanical, Medical and Process Engineering

Children's health law

Associate Professor Shih-Ning Then is interested in talking to students with interests in the areas of consent to treatment, special medical procedures, parental decision-making in health care, bioethics, assisted reproductive technology, pre-implementation genetic diagnosis (PGD) and embryo selection, or children as tissue donors.

Study level
PhD, Master of Philosophy
Faculty
Faculty of Law
Lead unit
Australian Centre for Health Law Research

A biofabrication surgical referral suite to predict intracranial aneurysm rupture

Intracranial aneurysms are bulging, weak areas of an artery that supply blood to the brain which are relatively common. While most aneurysms do not show symptoms, 1% spontaneously rupture which can be fatal or leave the survivor with permanent disabilities. This catastrophic outcome has motivated surgeons to operate on approximately 30% of aneurysms despite their rate of complications arising and cost of operation.The impact of aneurysm morphology on blood flow shear stress and rupture could educate surgical decision-making and better …

Study level
PhD, Master of Philosophy, Honours, Vacation research experience scheme
Faculty
Science and Engineering Faculty
Lead unit
School of Mechanical, Medical and Process Engineering

Portable magnetic resonance imaging of biological tissues

Magnetic Resonance Imaging (MRI) provides a unique way of non-invasive investigation of the 3D organisation of biological tissues and materials.The physical basis of MRI is the intrinsic magnetism of atomic nuclei. The magnetic moment of a single atomic nucleus is extremely small and effectively undetectable. However, the collective magnetisation of nuclei in a macroscopic sample can be sufficiently large to be detected, especially in the case of nuclei that are abundant in the sample. This is the case in most …

Study level
PhD, Master of Philosophy, Honours
Faculty
Science and Engineering Faculty
Lead unit
School of Chemistry and Physics

Involuntary Treatment for Mental Illness: Under what circumstances is it ethically justified?

Dr Sam Boyle is looking for candidates wanting to explore the ethical and legal issues associated with providing involuntary treatment for people with mental illnesses. Candidates may explore this issue in relation to ethics, human rights, or any other relevant angle, including an international comparative approach.

Study level
PhD, Master of Philosophy, Honours
Faculty
Faculty of Law
Lead unit
Australian Centre for Health Law Research

The use of PET-MRI in radiotherapy treatment planning

PET/CT is frequently used to assist in the planning of radiotherapy treatments. The PET information can help with determining the extent and function of the tumour as well as possible involvement of lymph nodes. This could result in improved targeting of the radiation to the disease.PET/MRI offers a number of advantages over PET/CT for head and neck cancer radiotherapy treatment planning. The MRI offers superior soft tissue contrast and no ionising radiation dose compared to the current standard of care, …

Study level
PhD, Master of Philosophy, Honours
Faculty
Science and Engineering Faculty
Lead unit
School of Chemistry and Physics

Medical selfies and patient generated health data

Smartphones and wearable technologies provide exciting opportunities for patients and health professionals to transform healthcare.Patients can benefit from photos (“medical selfies”) taken on their smartphone to record a condition that they want to discuss with a health professional. Wearable devices allow patients to semi-automatically collect data about their physical activity, sleep, mood, diet, etc.This data can help patients to better understand a health concern, its underlying causes and the impact of treatments.Clinicians, on the other hand, can benefit from medical …

Study level
PhD, Master of Philosophy, Honours
Faculty
Science and Engineering Faculty
Lead unit
School of Computer Science

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