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High-performance scoring of CRISPR targets

The CRISPR-Cas9 technology allows the modification of virtually any gene in any organism of interest. It's generated a lot of interest, both in the research community and the general population.One of the crucial components of CRISPR experiments is the design of the "guide RNAs" that will control where modifications occur. It's vital that the modification is made at the desired location and not elsewhere.We developed a method utilising high-performance computing to efficiently assess the "off-target risk" of each guide RNA …

Study level
Honours, Vacation research experience scheme
Science and Engineering Faculty
School of Computer Science
Research centre(s)
Centre for Data Science

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