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Humanized models for pre-clinical osteosarcoma research
Osteosarcoma (OS) is the most commonly occurring malignant bone tumour, predominantly affecting children and adolescents. Most OS patients are treated with a combination of surgery (tumour resection) and systemic chemotherapy with Doxorubicin.Unfortunately local recurrence and subsequent metastatic spread still frequently occurs, with an ultimate five-year survival rate of only around 25% once metastasis has occurred. There has been no progress in the enhancement of overall OS patient survival in the last four decades. One of the main reasons for this …
- Study level
- PhD, Master of Philosophy
- Faculty
- Science and Engineering Faculty
- School
- School of Mechanical, Medical and Process Engineering
- Research centre(s)
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