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Phylogenetic comparison between clonal P. aeruginosa strains and global, clinical strains of P. aeruginosa

Study level

Master of Philosophy

Honours

Vacation research experience scheme

Faculty/Lead unit

Topic status

We're looking for students to study this topic.

Supervisors

Dr Mark Harrison
Position
Senior Research Fellow
Division / Faculty
Science and Engineering Faculty
Professor Flavia Huygens
Position
Associate Director, IHBI (QIMR-B)
Division / Faculty
Faculty of Health

Overview

QUT researchers have recently sequenced the genomes of a selection of clonal P. aeruginosa strains that are know to cause severe hospital-acquired infections in the United Kingdom and Australia.

The phylogenetic relationship between these strains and other global, clinical P. aeruginosa strains is unclear.

Research activities

You will have the opportunity to use a wide range of bioinformatics tools to interrogate the genomes of the clonal P. aeruginosa strains and establish their phylogenetic relationship with known environmental, community and clinical strains.

Outcomes

The aim of the project is to understand the genetic relationships between virulent, clinical P. aeruginosa strains in the QUT collection and all other P. aeruginosa strains for which genomic DNA sequence information is available.

Skills and experience

To be considered for this project, you should have knowledge in the following scientific fields and strong practical skills would be well regarded:

  • bioinformatics
  • bacterial genetics
  • molecular biology.

Scholarships

You may be able to apply for a research scholarship in our annual scholarship round.

Annual scholarship round

Contact

Contact Mark Harrison for more information.