Study level

Vacation research experience scheme

Faculty/School

Topic status

We're looking for students to study this topic.

Supervisors

Dr Nathan Boase
Position
Lecturer
Division / Faculty
Faculty of Science
Associate Professor Emilie Sauret
Position
Associate Professor
Division / Faculty
Faculty of Engineering

Overview

In 2020, the impact of emerging viral infections on human health and socioeconomic development has been made glaringly apparent by the COVID-19 pandemic, caused by SARS-CoV-2. While SARS-CoV-2 is having a global impact, other viral infections are major contributors to morbidity and mortality around the world. Therefore, we need to have broad spectrum therapeutics on hand that can reduce disease severity, regardless of which viral strain causes the next pandemic.

This project aims to develop broad spectrum antiviral polymeric nanoparticles, to provide a platform technology for the treatment of emerging viral diseases.

Research activities

  • Carry out literature review.
  • Perform numerical simulations.
  • Report results and findings.

Outcomes

This undergraduate research project will aim to address the question: can virucidal polymers interfere with membrane fusion between the virus and the host cell? To achieve this, you will use coarse grained numerical modelling to investigate interactions between polymers and viral membranes and investigate how different physical and chemical properties of the polymers can improve these interactions.

Skills and experience

  • Strong interest on numerical modelling
  • Some experience in programming (MATLAB, C++)
  • Interest in chemistry

Keywords

Contact

Contact the supervisor for more information.