In 2020, the impact of emerging viral infections on human health and socioeconomic development has been made glaringly apparent by the COVID-19 pandemic, caused by SARS-CoV-2. While SARS-CoV-2 is having a global impact, other viral infections are major contributors to morbidity and mortality around the world. Therefore, we need to have broad spectrum therapeutics on hand that can reduce disease severity, regardless of which viral strain causes the next pandemic.
This project aims to develop broad spectrum antiviral polymeric nanoparticles, to provide a platform technology for the treatment of emerging viral diseases.
- Carry out literature review.
- Perform numerical simulations.
- Report results and findings.
This undergraduate research project will aim to address the question: can virucidal polymers interfere with membrane fusion between the virus and the host cell? To achieve this, you will use coarse grained numerical modelling to investigate interactions between polymers and viral membranes and investigate how different physical and chemical properties of the polymers can improve these interactions.
Skills and experience
- Strong interest on numerical modelling
- Some experience in programming (MATLAB, C++)
- Interest in chemistry
Contact the supervisor for more information.