There is increasing interest in developing 3D tumour models for use in cancer research. The models have been used to investigate and test novel therapies in a model that is closer to the in-vivo tumour micro-environment. So far there has been little investigation of their use for therapeutic interventions that include ionising radiation. This research will investigate how they may be used for studying the fundamental radiobiology of radiotherapy treatments for cancer.
In this research you contribute to developing techniques for growth of the models and workflows for irradiating with clinically-relevant ionising radiation beams. There will also be opportunities for monte-carlo modelling of the radiation interactions with cells using the TOPAS n-bio monte-carlo code.
The project(s) will involve collaboration between medical engineers, physicists and clinicians.
Outcomes could include, depending on scope and timeframe:
- peer-reviewed research papers
- conference presentations
- improvements in radiotherapy treatments for cancer.
Skills and experience
It would be considered favourable to have experience in the following areas:
- (medical) physics
- medical engineering
- data analysis.
You may be able to apply for a research scholarship in our annual scholarship round.
Contact the supervisor for more information.