Study level

PhD

Master of Philosophy

Honours

Vacation research experience scheme

Faculty/School

Science and Engineering Faculty

School of Chemistry and Physics

Topic status

We're looking for students to study this topic.

Supervisors

Dr Nathan Boase
Position
Lecturer
Division / Faculty
Science and Engineering Faculty
Professor Kathryn Fairfull-Smith
Position
Future Fellow
Division / Faculty
Science and Engineering Faculty

Overview

We have recently shown that nitroxides (sterically hindered versions of nitric oxide) can inhibit bacterial biofilm formation and disperse existing biofilms. Furthermore, nitroxide-containing antibiotics can eradicate mature biofilms. Bacteria, however, are rapidly becoming resistant to many antibiotics.

This project involves the synthesis, purification, characterisation and evaluation of new antimicrobials with less propensity for resistance development.

Research activities

In this research you will join a team of motivated PhD students to carry out:

  • the synthesis, purification and characterisation of small molecules and materials
  • an evaluation of antimicrobial properties.

Outcomes

New methods to treat infections, including infections associated with biofilms.

Skills and experience

You will need a good knowledge of organic chemistry and structural characterisation techniques.

Scholarships

You may be able to apply for a research scholarship in our annual scholarship round.

Annual scholarship round

Contact

Contact the supervisor for more information.