We have recently shown that nitroxides (sterically hindered versions of nitric oxide) can inhibit bacterial biofilm formation and disperse existing biofilms. Furthermore, nitroxide-containing antibiotics can eradicate mature biofilms. Bacteria, however, are rapidly becoming resistant to many antibiotics.
This project involves the synthesis, purification, characterisation and evaluation of new antimicrobials with less propensity for resistance development.
In this research you will join a team of motivated PhD students to carry out:
- the synthesis, purification and characterisation of small molecules and materials
- an evaluation of antimicrobial properties.
New methods to treat infections, including infections associated with biofilms.
Skills and experience
You will need a good knowledge of organic chemistry and structural characterisation techniques.
You may be able to apply for a research scholarship in our annual scholarship round.
Contact the supervisor for more information.