News

Koala vaccine for chlamydia close

17 July 2008

Eighteen female koalas treated with an anti-chlamydia vaccine are showing positive results, giving QUT scientists hope they have an answer to the disease that is threatening the survival of koalas in the wild.

Professors Peter Timms and Ken Beagley from Queensland University of Technology's Institute of Health and Biomedical Innovation (IHBI) said the vaccinated koalas, which are at Brisbane's Lone Pine Koala Sanctuary, were mounting a good response to the vaccine.

"A good T-cell immune response is essential if the vaccine is to be effective," Professor Timms said.

"This initial trial will measure only the animals' immune response and will not involve any live chlamydial infections.

"If all goes well with this trial our future studies will evaluate the vaccine on sick and injured koalas brought in for care, relocated animals, and koalas in other sanctuaries.

"As many as 25-50 per cent of koalas coming into care in both Queensland and NSW are showing clinical signs of the disease and it seems to be getting worse."

The researchers have also been working on developing a vaccine for the sexually transmitted disease chlamydia trachomatis in humans for many years.

"We've been able to develop the vaccine for koalas as a result of our studies on the development of human chlamydial vaccines done in the mouse model. We identified several novel vaccine proteins that we are trialling to protect koalas as well," Professor Beagley said.

He said chlamydia in koalas was a significant cause of infertility, urinary tract infections, and inflammation in the lining of the eye that often led to blindness.

"The number of koalas with chlamydia seems to be increasing and when combined with habitat destruction, chlamydial disease continues to be a major threat to koalas' survival," he said.

Professors Timms and Beagley said that despite the importance of developing a vaccine against chlamydia for koalas the team was struggling to raise enough funds to continue their work.

Media contact: Niki Widdowson, media officer, 07 3138 1841, 07 3138 1841 or n.widdowson@qut.edu.au.
** High res photo of Professor Timms and koala available for media use.

Professor Peter Timms and koala patient