Health

Tissue repair and regeneration

Overview

The research conducted by this area is focussed on tissue remodelling, especially as it pertains to extracellular environments and in particular, the interactions of growth factors and the extracellular matrix (ECM).

The research activity ranges from basic studies on pathogenesis, the molecular mechanisms underpinning these, through to targeted molecular, biochemical and cellular manipulation of cells and tissue to enable repair and regeneration. This has led to the generation of new devices and therapies, as well as prognostic and diagnostic tools to monitor tissue damage and repair.

Our researchers pursue interdisciplinary research, believing that innovative solutions are found at the interface between disciplines. Researchers have highly productive linkages with mathematical modellers, bio-informaticians, bio-engineers, biomaterials scientists, health economics experts, nurses and clinical specialists, and with biotechnology companies and health care service providers. These linkages have spanned the globe and involve industry partners, universities, hospitals and international research institutes.

Research programs

  • Tissue repair and remodelling
  • Skin and wound management

Infrastructure

  • Translational Research Institute (TRI)
  • PC2 (physical containment level 2) laboratories
  • Materials testing facilities

Performance

Evidence of research quality

ERA (Excellence in Research for Australia) 2015 scores:

  • 5 (well above world standard) -
    • Medical Biotechnology (FOR 1004)
  • 4 (above world standard) -
    • Biomedical Engineering (FOR 0903)
    • Nursing (FOR 1110)
    • Oncology and Carcinogenesis (FOR 1112).

ERA (Excellence in Research for Australia) evaluates the quality of research undertaken in Australian universities against national and international benchmarks.

Developing new researchers

Research students
31
Early career researchers
7

Publication output

2011

Unique count
Total
24
High quality
38%
Author weighting
Total
7
High quality
39%

Research income

2011 total
$1,133,754 (funding split)
2007-2011
$6,833,891 (funding split)

Key grants

  • VitroGro: Modern Wound Care Technology - Research-Industry Partnerships Program (RIPP)
  • Wound Management Innovation Cooperative Research Centre (CRC)

Partnerships

International linkages

  • Canada
  • Ireland
  • USA
  • Hong Kong
  • India
  • UK
  • New Zealand
  • Singapore

Cross-disciplinary engagement

  • Biology
  • Biochemistry
  • Biomaterials
  • Applied mathematics
  • Biomedical engineering
  • Nursing
  • Health services research
  • Materials engineering

Impact

Evidence of impact

  • Clinical development and trial of VitroGro products in conjunction with Tissue Therapies Ltd
  • Development of serum free culture technology
  • Development of novel 3D cell culture technology
  • Novel wound therapeutics and diagnostics
  • Improving clinical practice

Research enquiries

IHBI research enquiries

Contact us to find out about research and discovery at the Institute of Health and Biomedical Innovation (IHBI).