Dr Patrick Thomas
Faculty of Health,
School of Biomedical Sciences
Biography
Dr Patrick Thomas completed his PhD in prostate cancer genomics and molecular biology in 2018 and is now permanently located at the Translational Research Institute as a Research Fellow within the Queensland Bladder Cancer Initiative (QBCI) and Australian Prostate Cancer Research Centre. His research, currently supported by the PA Research Foundation, is focused on urological cancers and tumour immunology with the aim to develop a rapid in vitro model to predict therapy response in bladder and prostate cancer patients. Within the QBCI, Dr Thomas has established a comprehensive and contemporary bladder cancer tissue biobank to further enable Australian research in this space. Dr Thomas’ research interests center around precision medicine in cancer, including multiparametric immunophenotyping of bladder tumours, organoid co-culture models of urological cancer and spatial profiling of histologically divergent bladder cancers. Dr Thomas has won over 10 national and international awards for cancer research excellence and is the EMCR representative for QUT scholarly communications. He is a proud 9-year Movember veteran, lecturer and sessional academic and Director of Prostate Awareness Australia.Personal details
Positions
- Visiting Fellow
Faculty of Health,
School of Biomedical Sciences
Keywords
Bladder cancer, Prostate cancer, Precision medicine, immunooncology, cancer genomics, noncoding RNA, microbiology in carcinogenesis, 3D cell biology
Research field
Oncology and Carcinogenesis, Biochemistry and Cell Biology, Medical Microbiology
Field of Research code, Australian and New Zealand Standard Research Classification (ANZSRC), 2008
Qualifications
- PhD (Queensland University of Technology)
- Bachelor of Applied Science (Honours) (Queensland University of Technology)
Professional memberships and associations
Australian Society for Medical Research (ASMR)
The Endocrine Society of Australia
American Association for Cancer Research
Australian Institute of Medical and Clinical Scientists
SoBMS EMCR Committee
Translational Research Institute Postdoc Network
Office of Scholarly Communications Advisory Committee
Chair of the EMCR Scholarly Community of Practice
Teaching
An active academic within the Faculty of Health over 10-years, Dr Thomas has taught into over 10 health science disciplines within the Bachelor of Applied Science (Medical Science) and Bachelor of Biomedical Science. His teaching has been recognised with the award of Fellowship of the Higher Education Academy and nomination for the QUT David Gardener of the year award, awarded for teaching excellence at a University wide level
Experience
Dr Thomas is the director for not-for-profit charity group, Prostate Awareness Australia (PAA), who strive to provide education and awareness for building and construction industries in Queensland.
Publications
- Maugham, M., Seim, I., Thomas, P., Crisp, G., Shah, E., Herington, A., Gregory, L., Nelson, C., Jeffery, P. & Chopin, L. (2019). Limited short-term effects on human prostate cancer xenograft growth and epidermal growth factor receptor gene expression by the ghrelin receptor antagonist [D-Lys3]-GHRP-6. Endocrine, 64(2), 393–405. https://eprints.qut.edu.au/128162
- Thomas, P., Seim, I., Jeffery, P., Gahete, M., Maugham, M., Crisp, G., Stacey, A., Shah, E., Walpole, C., Whiteside, E., Nelson, C., Herington, A., Luque, R., Veedu, R. & Chopin, L. (2019). The long non-coding RNA GHSROS facilitates breast cancer cell migration and orthotopic xenograft tumour growth. International Journal of Oncology, 55(6), 1223–1236.
- Tian, R., Geng, Y., Thomas, P., Jeffery, P., Mutton, T., Chopin, L., Baker, A. & Seim, I. (2019). The mitochondrial genome of the black-tailed dasyure (Murexia melanurus). Mitochondrial DNA Part B: Resources, 4(2), 3598–3600. https://eprints.qut.edu.au/133719
- Maugham, M., Seim, I., Thomas, P., Crisp, G., Shah, E., Herington, A., Brown, K., Gregory, L., Nelson, C., Jeffery, P. & Chopin, L. (2018). No effect of unacylated ghrelin administration on subcutaneous PC3 xenograft growth or metabolic parameters in a Rag1-/- mouse model of metabolic dysfunction. PLoS One, 13(11). https://eprints.qut.edu.au/123452
- Maugham, M., Thomas, P., Crisp, G., Philp, L., Shah, E., Herington, A., Chen, C., Gregory, L., Nelson, C., Seim, I., Jeffery, P. & Chopin, L. (2017). Insights from engraftable immunodeficient mouse models of hyperinsulinaemia. Scientific Reports, 7, 1–10. https://eprints.qut.edu.au/108590
- Seim, I., Jeffery, P., Thomas, P., Nelson, C. & Chopin, L. (2017). Whole-genome sequence of the metastatic PC3 and LNCaP human prostate cancer cell lines. G3: Genes, Genomes, Genetics, 7(6), 1731–1741. https://eprints.qut.edu.au/105844
- Seim, I., Jeffery, P., Thomas, P., Walpole, C., Maugham, M., Fung, J., Yap, P., O'Keeffe, A., Lai, J., Whiteside, E., Herington, A. & Chopin, L. (2016). Multi-species sequence comparison reveals conservation of ghrelin gene-derived splice variants encoding a truncated ghrelin peptide. Endocrine, 52(3), 609–617. https://eprints.qut.edu.au/92200
- Chopin, L., Crisp, G., O'Keeffe, A., Kimlin, M., Stacey, A., Anderson, D., Seib, C., Whiteside, E., Humphreys, J., Lee, K. & Thomas, P. (2014). A longitudinal study of the impact of chronic psychological stress on health-related quality of life and clinical biomarkers: protocol for the Australian Healthy Aging of Women Study. BMC Public Health, 14, 1–8. https://eprints.qut.edu.au/66089
- Whiteside, E., Seim, I., Pauli, J., O'Keeffe, A., Thomas, P., Carter, S., Walpole, C., Fung, J., Josh, P., Herington, A. & Chopin, L. (2013). Identification of a long non-coding RNA gene, growth hormone secretagogue receptor opposite strand, which stimulates cell migration in non-small cell lung cancer cell lines. International Journal of Oncology, 43(2), 566–574. https://eprints.qut.edu.au/68092
QUT ePrints
For more publications by Patrick, explore their research in QUT ePrints (our digital repository).
Supervision
Current supervisions
- Development of a Personalised Immuno-oncology Testing Platform
MPhil, Principal Supervisor
Other supervisors: Associate Professor Elizabeth Williams, Professor Tony Kenna - Defining the tumour-immune microenvironment of bladder cancer using multiplexed spatial proteomics and multiparametric flow cytometry
MPhil, Principal Supervisor
Other supervisors: Associate Professor Elizabeth Williams, Dr Arutha Kulasinghe, Professor Tony Kenna