Overview
Topic status: We're looking for students to study this topic.
The carrier widely used in DPIs is lactose and its physico-chemical characteristics like particle size, shape, surface roughness and adhesional forces influence the drug dispersion. Despite several attempts to modify lactose with a view to increase efficiency of DPI system having been carried out, the maximum performance of drug delivery to the deep lungs could not be achieved and therefore, exploring suitable alternative carriers for DPIs is essential. The objective of this study is to use biodegradable polymers as alternative carriers to lactose in DPIs for achieving efficient drug delivery into the lungs. This project focuses on producing biodegradable polymer particles with controlled surface morphology and defined shape to maximize drug delivery. The physicochemical properties and surface characteristics of polymeric carrier particles will be probed by surface analytical methods (AFM, XPS, etc) to get a better understanding of the influence of these factors in affecting the drug dispersion.
- Study level
- PhD
- Supervisors
- QUT
- Organisational unit
Science and Engineering Faculty
- Research area
- Contact
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Please contact the supervisor.
Dr Nazrul Islam
