Overview
Topic status: We're looking for students to study this topic.
We have collaborated with neurology clinical and research specialists at the Royal Brisbane and Women's Hospital in order to develop better methods for identifying and counting the number of functioning motor units serving a particular muscle, motor unit number estimation (MUNE). Loss of muscle force can be due to a loss of upper and/or lower motor neurons. This project will involve investigation of upper motor neurons in the brain using MRI data with the goal that robust markers of disease progression can be used to measure the efficacy of new treatment strategies. For example, the way the brain connects with one part and another can be described by a connectivity matrix or connectome but the values of this are subject to various sources of noise and these need to be determined and quantified in order to make this a useful concept. The project will review the literature and current methods and software for fitting MRI data. It will also consider the connectome and ways of smoothing (removing noise) and modelling its information so that it provides a useful diagnostic tool.
- Study level
- Honours
- Supervisors
- QUT
- Organisational unit
Science and Engineering Faculty
- Research area
- Keywords
- statistics
- Contact
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Please contact the supervisor.
Professor Tony Pettitt
