Overview

Topic status: We're looking for students to study this topic.

The HtrA protease has been established to have a function in infection of human macrophages by Legionella pneumophila. However, the exact function of the protease remains to be elucidated. The project will involve a search for protease substrates of HtrA using in vitro approaches. The specific role of each of these substrates for Legionella pathogenesis will then be investigated using a variety of in vitro and in vivo techniques. This molecular microbiology project will provide high quality training in molecular biology and pathogenesis.

Study level
PhD, Masters
Supervisors
QUT
Organisational unit

Science and Engineering Faculty

Research area

Cell and Molecular Biosciences

Contact
Please contact the supervisor for enquiries.