Cell and molecular biosciences
Overview
The discipline comprises four major programs:- Tissue Repair and Regeneration
- Infectious Diseases
- Hormone Dependent Cancer Research
- Applied Microbiology
Much of the discipline's research around Tissue Repair & Regeneration, Infectious Diseases and Hormone Dependent Cancer is carried out within the Institute for Health & Biomedical Innovation. Other discipline staff work within the Australian Prostate Cancer Research Centre - Queensland (APCRC-Q) which employs a transdisciplinery approach to prostate cancer research.
Grants and projects
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Student topics
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- Cartilage tissue engineering
- EphB4-eprhinB2 signaling in prostate cancer
- Bioreactors for Cartilage Regeneration
- Chlamydia and infertility in women; diagnostics
- The role of SASH1 in genomic stability
- Scaffolds for Skin Regeneration
- Investigating the role of FGFR2 in endometrial cancer
- Chlamydia and infertility in women; epidemiological data
- Haematopoietic Stem Cell Cellular Therapies
- Trace DNA from smudges
- Infection-mediated exacerbation of asthma
- hSSB1 Mutations in Cancer
- Bone Histology Techniques - Compare and Contrast
- Synthetic Lethality in Cancer
- Micro RNA’s in epithelial wound healing
- Population Dynamics of Mosquito-Borne RNA Viruses
- Determination of the role of HtrA in pathogenesis of Legionella pneumophila
- Clinical role of chlamydia extracytoplasmic proteins during infertility
- Biochemical Characterisation of the Substrates and Specificity of Chlamydia trachomatis Virulence Protease HtrA
- Importance of chlamydial infections in wildlife
- Diagnosis and Early Intervention of Schizophrenia
- Ureaplasma Infection and Reproductive Health
- Extracellular production by ovarian cancer cells
- Characterisation of the biochemical mechanisms and substrates of extracytoplasmic proteases from Legionella
- Characterisation of the Biochemical Mechanisms and Substrates of Extracytoplasmic Proteases from Legionella
- Role of Epithelial to Mesenchymal Transition in Wound Healing
- Bioreactors for Blood Stem Cell Production and Micromarrows
- Discovery of proteomic biomarkers of musculoskeletal injury
- Towards Improved Blood Vessel Generation to Heal Wounds
- Biochemical characterisation of chronic wounds
- DNA methylation–based biomarkers for the early detection of metastatic breast cancer
- Characterisation of hSSB1 ubiquitination sites and their biological function
- Exploring New Treatments for Bone Metastatic Lesions
- Next Generation Protein-based Wound Healing Therapeutics
- Targeting cancer stem cells in the treatment of prostate cancer
- Investigating mechansims of intrinsic resistance to FGFR inhibition
- Identification of Novel Cancer-Associated Protein Kinases
- Electrospinning polymer fibres with bioglass particles to enhance bone-cell attachment, proliferation and differentiation
- Fibronectin:Growth Factor Chimeric Proteins for Use as Potential Wound Healing Agents
- The Role of DNA Repair Proteins in Blood Cancers
- To assess the role of FGF signalling molecules in prostate cancer associated fibroblasts
- Investigating mechanisms of acquired resistance to FGFR inhibitors
- Identifying mutations that provide resistance to the clinically relevant FGFR inhibitor Ponatinib
- Serine Protease Regulation of EphB4-ephrinB2 Signaling in Prostate Cancer
- Isolation and identification of microorganisms in human Fallopian tubes
- Investigations into the Mechanisms Underlying the Enhanced Wound Healing Stimulated by Novel Growth Factor Complexes
- To generate and characterize primary immortalized endometrial epithelial cell with defined oncogenic aberrations
- Towards enhanced wound healing through analysis of TMEM26 knock–out mice
- Structure/Function Determination of Chimeric VN:IGF-I Growth Factor Components
- Forensic collection and profiling of DNA from hard surfaces
- To generate unique patient-derived xenograft models of endometrial cancer and utilize them in preclinical studies with emerging targeted agents to identify biomarkers of response
- Understanding Staphylococcus aureus Pathogenesis: Community- Acquired vs Hospital-Acquired
- EphB4 and Src signalling in cancer: can we beat it with dasatinib?
- Establishment of Immunohistochemistry Techniques for the Characterisation of Soft Tissue Trauma
- Recombinant Chimeric Proteins as Potent Stimulators of Angiogenesis to Heal Wounds
- Proteomic analysis of human keratinocyte culture for clinical applications
- Is SUMO Bringing EphB4 into the Nucleus of Prostate Cancer Cells?
- Proteomic Characterisation of Soft Tissue Injuries in a Rat Model
- Investigation of the Effects of Hyperbaric Oxygen Therapy on Epidermal Formation using a 3D Human Skin Equivalent Model
- Exploring Tumour Environmental Influences on Ovarian Cancer
- Improved Diagnostic and Prognostic Indicators for Breast Cancer Progression and Patient Outcome
- Investigating the Mutational and Non-Mutational Mechanisms of Resistance to Anti-FGFR Inhibitors
- Comparative end–point proteomics: a new approach for understanding psoriasis and therapeutic target mining
- Isolation and Identification of Protein Biomarkers of Musculoskeletal Injury and Physical Activity
- Proteomic Analysis of Tissue Degenerative Disease in an Equine Model
- Investigation of Mechanisms Underpinning Keratinocyte Re-Epithelialisation During Wound Healing Using 3D Human Skin Equivalent Models
- Spatial and Structural Considerations that Affect Protein:Protein and Protein:Receptor Interactions
- Metabonomic analysis of biological samples using NMR as a tool for identifying prostate cancer
- The role of the Insulin–like Growth Factor (IGF) system in latent Transforming Growth Factor–beta 1 (TGF–β1) activation and function
- Metabonomic Analysis of Biological Samples Using NMR as a Tool for Identifying Prostate Cancer
- To Identify the Molecular Mechanism by Which Several Novel Endometrial Cancer Associated FGFR2 Mutations Result in Receptor Activation
- Does C. pneumoniae infection of atopic dendritic cells promote a Th2 phenotype that exacerbates asthma?
- Discovery of Diagnostic Biomarkers of Anterior Cruciate Ligament Injury & Repair
- Inducement of Cancer in Normal Breast Epithelial Cells by Fibroblast- Specific Over Expression of EMT Genes
- Application of a 3-D Culture Platform to an In Vivo Ovarian Cancer Model
- Production and Optimisation of Q-ConCAT SRM Standards for Biomarkers of Physical Activity
- Quantification of Differences in Downstream Signaling from Pathogenic FGFR2 Mutations Located in Different Functional Domains
- The Extracellular Matrix of Ovarian Cancer
- Co-culture of Ovarian Cancer and Stromal Cells Using a Novel 3-D Model
- Development of Reagents to Measure the Immune Response of the Koala
- Investigating the Role of the IGF-1R in Breast Cancer Stem Cells
- The Relationship between Chronic Chlamydial Infection and Irritable Bowel Syndrome (IBS)
- The effect of ADAM 10 inhibition on the metastatic potential of melanoma cells
- Understanding the Genetics of Prostate Cancer with an Emphasis on Kallikreins
- Molecular epidemiology of koala chlamydial infections on the Koala Coast
- Modelling of EMT (Epithelial-Mesenchymal Transformation) in Wound Healing
- Uncovering the Downstream Effectors of FOXC2 in Basal Breast Cancer
- Retention of Coxiella burnetii in Soil - Is Property Development of Former Livestock Properties a Safe Practice?
- Viable and Dead Bacterial Cells in Water: Development of a Novel Way to Accurately Assess Water Quality and Human Health Risk
- Understanding the role of tumour microenvironments on ovarian cancer phenotypes
- Identification of Novel Therapeutic Targets to Inhibit Melanoma Metastasis
- Investigations into the Effectiveness of Antibiotic Treatment for Chlamydia trachomatis STD Infections in Humans
- One-step further towards vascularisation of tissue engineered scaffolds
- Utilising a Human Skin Model to Optimise Transcutaneous Delivery as a Vaccine Strategy
- Identification of bioactive compounds in Aboriginal medicinal plants and their effects on wound healing
- Better Skin: Refinement of Human Keratinocyte Culture for Clinical Applications
- Determining the functional significance of ADAM-10 expression by malignant trophoblast cells during the Epithelial to Mesenchymal Transition (EMT) and the processes of cell migration and cell invasion
- EphB4 as a therapeutic target in breast cancer: Monoclonal antibody screening using a 3D biomimetic model
Research degree enquiries
Science and Engineering research office
- Phone: 3138 4783
- Int. phone: +61 7 3138 4783
- Email: sef.research@qut.edu.au
Commercial research enquiries
Science and Engineering Faculty - Commercial Research and Corporate Education
- Phone: 3138 9948
- Int. phone: +61 7 3138 9948
- Email: sef.industryenquiry@qut.edu.au
Partnership enquiries
Science and Engineering - Partnerships
- Phone: 3138 7693
- Int. phone: +61 7 3138 7693
- Email: sef.industryenquiry@qut.edu.au
